Generating Human Pancreatic Tissue Slices to Study Endocrine and Exocrine Pancreas PhysiologyJulia K. Panzer 1, Pablo A. Garcia 1, Alberto Pugliese 1
1Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute
This protocol describes how to generate human pancreas slices from deceased organ donors to study cell function under near-physiological conditions. This innovative approach enables the investigation of normal and structurally damaged islets and the intricate interplay between endocrine and exocrine compartments.